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Green et al 26 Severe clinical abnormalities should be treated intensively with B 12 , cyanoB 12 or hydroxyB 12 : HydroxyB 12 is commonly used in Europe, often at intervals of 23 months, as it seems to have better retention than cyanoB 12

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Together, these results demonstrate that X(PC) remains catalytically active when expressed in mammalian cells and can cleave full-length procaspase-1 even in the presence of the endogenous intracellular human proteome