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Compulsory licensing has been most prominently used for HIV/AIDS antiretrovirals and, more recently, was the subject of significant debate during the COVID-19 pandemic
For most patients at 0.5 mg who have not achieved treatment goals, the appropriate next step is increasing to 1 mg weekly after at least four weeks at the current dose, provided the medication is well-tolerated
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ATTAIN-1 was a 72-week, randomized, double-blind, placebo-controlled trial comparing the efficacy and safety of orforglipron (6 mg, 12 mg, and 36 mg) as monotherapy vs
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