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The pivotal redox-sensitive transcription factor is nuclear factor erythroid 2-related factor 2 (Nrf2) 19 , recognized as the leading transcription factor driving the antioxidant response in cancer cells
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In vitro studies, HepG2 cells treated with palmitic acid (PA) were found that dulaglutide significantly reduced liver lipid accumulation and gene expression related to lipid drop-binding proteins, de novo adipogenesis and TG synthesis
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