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Regulating melanin production, which can influence skin tone and pigmentation
A drug can not generally have an oral bioavailability value higher than its value for f H , and oral bioavailability can equal f H only when all of the drug escapes from the GI tract and is able to enter the portal circulation (i.e
Nutr Res 46:2230 Wang QP, Browman D, Herzog H, Neely GG (2018) Non-nutritive sweeteners possess a bacteriostatic effect and alter gut microbiota in mice
This study lacked a placebo control, so results should be interpreted cautiously
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