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This superior efficacy helped it achieve global sales of ~US$16.4bn in 2024 (Mounjaro ~US$11.5bn and Zepbound ~US$4.9bn), rivalling semaglutide and completely overshadowing the sales of historical GLP-1s, such as exenatide, liraglutide and dulaglutide [FIGURE TWO]

When the medication mutes your desire for food, it regularly mutes your desire for fluids right along with it

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Patients face these permanent life-altering consequences from NAION-related blindness: Sudden blindness in affected eye: Most experience dense altitudinal visual field loss affecting top or bottom half, with some suffering complete blindness Inability to drive or work: Vision loss severe enough to disqualify from driving and render many occupations impossible Constant risk to fellow eye: Living with approximately 15% risk over five years that the second eye will suffer identical fate No restorative treatment options: Unlike cataracts, NAION leaves patients with zero medical solutions for recovery Permanent disability from NAION has made these injuries central to litigation