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In a research letter published in JAMA Network Open in August, the authors purchased off-brand forms of semaglutide from six online pharmacies

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The researchers employed an eight-week dose escalation regimen at the start of treatment, with dose escalation (as tolerated) from 0.25mg/week for four weeks to 0.5mg for four weeks, followed by a maintenance dose of 1mg/week throughout the remainder of the treatment period, as they stated in their article