FIGURE 2 The primary ROS produced by the ETC is superoxide, a free radical with moderate reactivity, whose generation can lead to more reactive or secondary ROS derivatives
In the acute inflammatory stage, N1 neutrophils are dominant and release reactive oxygen species and proteases, such as matrix metalloproteinase-8 (MMP-8) and MMP-9, which are involved in the killing of pathogens (120)
GLP-1 Side Effects at a Glance Nausea & vomiting Constipation Diarrhea Reflux & sulfur burps Loss of muscle and lean mass Skin, hair, and nail changes Fatigue, depression, and the blahs Dehydration Less Common but Serious Side Effects Pancreatitis and pancreatic cancer Gallstones & gallbladder disease Thyroid cancer Acute kidney injury Retinopathy, macular degeneration, and nonarteritic anterior ischemic optic neuropathy (NAION) Common GLP-1 Side Effects and How to Manage Them Most side effects show up early, often within the first few days of beginning GLP-1 treatment
CNS Drugs 22 , 389406 (2008)