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10.1186/1742-2094-5-19 41 HayesM
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So far, semaglutide (Wegovy) shows the most significant weight loss among approved GLP-1s: Average weight loss: 15 percent or more of body weight over time Administered once weekly Tirzepatide (Mounjaro), though not a pure GLP-1, has shown even greater weight loss in trials and was approved by the FDA specifically for weight management under the name Zepbound
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