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Under hypoxic conditions, HIF-1-induced lactate alters intracellular pH, reduces the release of free Fe 2 , and enhances the SLC7A11 system, thereby increasing cellular resistance to ferroptosis [63]
326,327 While ChREBP deficiency improves IR and hepatic steatosis by inhibiting the entire lipogenic and esterification process
Insight on the order of regioselective ultrafast formation of disulfide bonds in (antimicrobial) peptides and miniproteins
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