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For instance, the Ames and Snell mice, which are deficient for GH signaling, and the little mice with a mutation in the growth hormone-releasing hormone receptor ( GHRHR ) gene, are typical long-lived mouse models

DOI: 10.1182/blood-2011-07-356006 5

Addition of 2 mM PPG resulted in the decrease of the intracellular taurine levels: from 10.25 5.00 observed in control, to 2.53 0.68 nmol/mg protein (24 h of culture) and from 17.06 9.40 to 2.43 0.26 nmol/mg protein (control vs