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Lauti M, Kularatna M, Hill AG, MacCormick AD
Tirzepatides dual mechanism tends to produce larger average weight loss in clinical trials, which may be an advantage for adults over 50 who face greater metabolic resistance
Moreover, treatment with mitochondria-targeted antioxidant MitoQ preserves mitochondrial quality control, alleviates tubular injury, and restores kidney function by reversing mitophagy deficiency through the Nrf2/PTEN-induced kinase 1 (PINK) signaling pathway in db/db mice (68)
doi: 10.1016/j.brainres.2014.12.045 59 XiaWMaoYXiaZChengJJiangP
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