Safety, Eligibility, and When to Seek More Intensive Screening Both platforms screen for GLP-1 contraindications: personal or family history of medullary thyroid cancer, multiple endocrine neoplasia type 2, severe pancreatitis, and severe kidney disease
Front Aging Neurosci 10:106 Frantseva MV, Velazquez JL, Hwang PA, Carlen PL (2000) Free radical production correlates with cell death in an in vitro model of epilepsy
Warning: Risk of Thyroid C-Cell Tumors In studies with mice and rats, semaglutide (the active ingredient in Wegovy and Ozempic) caused thyroid tumors, including thyroid cancer
Here's what you need to know: Medicare Coverage (Effective Mid-2026) Following the November 2025 Trump administration agreements, Medicare will cover GLP-1 medications for obesity with: $50 monthly copay for eligible patients $245 government cost (down from $1,000+ list prices) Medicare Eligibility Requirements: BMI over 27 with prediabetes OR established cardiovascular disease, OR BMI over 30 with uncontrolled hypertension, kidney disease, or heart failure, OR BMI over 35 (severe obesity) Medicaid Coverage States can opt into $245 monthly pricing for all covered uses