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Preclinical studies investigating KD in HD have primarily used transgenic mouse models, such as the R6/2 mice, which express mutant huntingtin and exhibit progressive motor deficits, weight loss, cognitive impairment, and mitochondrial dysfunction, mimicking central functional and metabolic aspects of HD progression [95, 96]
Topical GSH can be used alongside mild pigment inhibitors, such as arbutin or tranexamic acid
N-Acetyl Cysteine (NAC) 25 mg
- A body lotion helps replenish skin condition with deep hydration to repair irritated skin
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