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Close glucose monitoring is advisable, particularly for patients on multiple diabetes medications
The 48-week retatrutide curve had not plateaued at readout, so the 24.2% figure likely under-represents the 72-week steady state that would match SURMOUNT-1's window [1]
Understanding the specific molecular differences explains why one requires daily injections and the other works once a week
Studies report minimal adverse events compared to more aggressive fasting schedules
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