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Inclusion criteria This review considered peer-reviewed studies of L-carnitine supplementation in subjects with coronary artery disease across predefined designs, each with a distinct role, including preclinical evidence such as animal studies which provided mechanistic evidence and insights on emerging pathways, as well as clinical evidence such as case reports, cross-sectional studies, observational studies, retrospective analyses, randomized controlled trials, systematic review and meta-analyses which provided primary evidence as well as quantitative analysis of clinical endpoints
Nausea becomes more common, particularly in the mornings and after meals containing fat
Common negative reports include increased injection site discomfort, slightly more GI upset (particularly during the first few weeks), and disappointment when the dramatic results promised by marketing materials do not materialize
Infection often causes severe pain, fever, fatigue, or symptoms that spread to other people nearby
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