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Patients should be advised to stop the medication and seek urgent medical attention (call 999 or attend A&E) if they experience severe, persistent abdominal pain
vascular and metabolic cognitive impairment A critical consideration is the potential incongruity between the pharmacological mechanism of a drug and the specific pathology of Alzheimers disease (AD)
GLP-1 is a peptide secreted by L-type enteroendocrine cells in the ileum and colon in response to different nutrients, mainly glucose and lipids, whereas glucose-dependent insulinotropic polypeptide is produced by K cells present in the duodenum and the first portion of the jejunum
Recent studies have shown that exendin-4 could improve hepatic steatosis by modulation of lipid metabolism and hepatic insulin signaling in ob/ob mice and in human hepatocyte [8,9]
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