Materials and methods Chemicals KH 2 PO 4 , MgCl 2 6H 2 O, FeCl 3 6H 2 O, NaH 2 PO 4 H 2 O, HCl, Na 2 CO 3 , Na 2 B 4 O 7 10H 2 O, ammonium persulfate and imidazole were purchased from Merck KGaA (Darmstadt, Germany)
Initially conceptualized as a therapeutic for neurodegenerative disorders such as Alzheimers and Parkinsons disease, its primary mechanism of action involves high-affinity binding to hepatocyte growth factor (HGF) and its cognate receptor c-Met
When phagocytosis lysosomes are formed, various membrane proteins, such as lysosomal Lys/Arg transporter LAAT-1, LMP 1, type II DNAse (NUC-1) and cathepsin L (CPL-1), are recruited, thus destroying and degrading apoptotic cells (Liu et al., 2012
This effect was observed across DSIP concentrations ranging from 10 to 10 M, showing a 10-20% elevation