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As the body ages, levels of key cellular nutrients like NAD+ and B12 naturally decrease, affecting how efficiently cells produce energy
Nutritional deficiencies can weaken the body's resistance and tissue repair capacity, severely hampering the recovery process
[8] [9] [10] Clinical significance [edit] The importance of the MC4R in the regulation of human body weight first became apparent in 1998 with the reports from two groups [11] [12] of single families in whom heterozygous frameshift mutations in MC4R cosegregated with dominantly inherited severe early-onset obesity
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