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Additionally, there was significant accumulation of Fe 2+ in the cytoplasm and decreases in the polar body (PB) expulsion rate and blastocyst formation rate

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Guan, C., Li, C., Shen, X., Yang, C., Liu, Z., Zhang, N., Xu, L., Zhao, L., Zhou, B., Man, X., Luo, C., Luan, H., Che, L., Wang, Y., & Xu, Y

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(2018) showed that metformin treatment altered the metabolism of folate and methionine in mice, which in turn inhibited the growth of B

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