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The results showed that tesofensine, particularly at a dose of 0.5 mg, led to a significant improvement in the total UPDRS score (-4.7 points) and a reduction in off time (-7.1%)

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A large real-world cohort of 547,993 matched patients (Vidal/Akiska et al., JAAD International 2026) showed, at 12 months, an increased risk of both telogen effluvium (raised by around 76%) and androgenetic alopecia (raised by around 64%)

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