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Hydrate well to minimize any side effects of medications and diminish water retention

Clinical trials, including the STEP program and a 2021 New England Journal of Medicine study on MASH, have documented reductions in alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels

However, although good metabolic control can reduce the risk of microvascular complications [2], its impact on cardiovascular morbidity and mortality is still a matter of discussion