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Compared to these upstream modulators, AOD 9604 occupies a more targeted position within this class, allowing researchers to isolate lipid metabolism signaling from broader GH-driven physiological processes
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In cognitive peptides: substitute when possible in vivo tests by cerebral organoids or primary neuronal cultures ( Replacement ), optimise experimental plan to minimise the number of animals ( Reduction ), use appropriate anaesthesia and analgesia during invasive procedures ( Refinement )
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