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The second omission is ignoring where oral dosing actually makes sense: local GI action
investigated in models of traumatic brain injury, Parkinsons-related pathways, and neurological inflammation Nitric oxide system interaction Proposed to modulate NO synthesis pathways
Both compounds independently cause nausea, vomiting, diarrhea, and constipation - especially during dose increases
Acknowledgements This work was supported by Chang Gung Memorial Hospital [CMRPG391311, CMRPG3A1131, CMRPG3H0611 and Grants CIRPD1D0071-3
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