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The recognition cements more than a decade of leadership for the San Clemente-based supplement company, which pioneered the topical vitamin patch format and has remained the standard-bearer for quality, innovation, and medical credibility in the category

[6] GHK-Cu and Pain Perception In rat models, the exposure of GHK-Cu was reported to exhibit a concentration-dependent impact on pain-induced behavior

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However, these are merely early signals, and robust finding regarding efficacy cannot be made until the results of larger randomized controlled trials with determining endpoints come about