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In HepG2 cells, L-carnitine reduced free fatty acid-induced apoptosis (72), while similar anti-apoptotic effects occurred in oleic acid-treated hepatocytes (77)

Molecular modelling of the FOXO4-TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells

So it was hypothesized there were some suite of mechanisms by which your gut actually signaled the rest of your body that you had eaten something

Recently, our group also showed that intraperitoneal injection of H 2 can alleviate acute ethanol-induced hepatotoxicity in mice partially via inhibiting Caspase-11 and Caspase-8 to GSDMD, and Caspase-3 to GSDME non-canonical pyroptosis signaling in the liver (Xu et al., 2024)