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Metabolic and bariatric surgery should be discussed with patients who have BMI 35 kg/m (regardless of comorbidities) or BMI 30-34.9 kg/m with metabolic disease, according to 2022 ASMBS/IFSO guidelines

Osmotic laxatives (such as polyethylene glycol or magnesium hydroxide) and stool softeners are typically lower-risk options because they work gently and don't interact directly with semaglutide's mechanism

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Personalized Semaglutide+ is a compounded formulation containing the same active pharmaceutical ingredient (semaglutide) found in the FDA-approved medications Wegovy and Ozempic