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In the long-term toxicity experiment, continuous injection of AOD 9604 (10 mg/kg) for 8 weeks did not cause abnormal liver and kidney functions or fluctuations in blood glucose, providing a safety basis for its further research and application

Still, increasing diversity in genetic research remains essential to ensure equitable advances in precision medicine

Moreover, periodic body composition assessment (e.g., through DXA or BIA) is advisable in order to early detect disproportionate loss of lean mass and to adapt nutritional interventions accordingly [42]

Research focus: initially explored in obesity and metabolic-syndrome models