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10% after 1+ year on therapy [5] Cigna Decision Timelines Standard review: 5-15 business days Expedited review: 24-72 hours (if medically urgent) Quantity Limits (Updated 2025-2026) Cigna enforces quantity limits based on dosage strength: [6] 7.5 mg and 12.5 mg pens: Limits tightened to every 21 days Re-initiation/re-titration: One-time overrides available for patients restarting therapy (additional 2 mL/4 pens may be approved) Renewal Requirement Don't Miss This Most Cigna plans require you to lose at least 5% of your starting body weight to continue coverage after the first authorization period (usually 6-12 months)
Formulations without preservatives must be used more quickly, often within days rather than weeks, because each puncture introduces potential contamination with no chemical defense against bacterial growth
Penick SB, Hinkle LE Jr
So, we had to quantify this evidence to show that it stemmed from the FDA approval and how to contain the risk
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