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Ferroptotic foam cells release substantial inflammatory mediators, including IL-1 and IL-18, which belong to the IL-1 cytokine family and undergo caspase-1-mediated activation (48, 49)
Elevated levels can disrupt your bodys natural ability to detoxify
Therefore newborn screening is essential for diagnosis and initiation of treatment, which prevents the devastating effects of infantile hyperphenylalaninemia
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