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Beyond its effects on the central nervous system, DSIP has been detected in peripheral organs, blood, cerebrospinal fluid, and even human breast milk, indicating a systemic physiological role

Additional preclinical themes include angiogenesis (through endothelial cell migration and tube formation), modulation of inflammatory signalling, and reported effects on cardiac, dermal and neural tissue in animal models

Clinical trial protocols from the Phase 2 NEJM study used a gradual escalation approach, starting at low doses and increasing every four weeks

Like many peptides, BPC-157 is a short chain of amino acids that is found naturally in the body