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This initiates the controlled release of imaging agents or chemotherapeutic drugs directly at the tumor location [109]
In addition to inhibiting oncogenic signals, these compounds often activate stressresponse pathways in cells
Con cetuximab se han descrito reacciones anafilcticas graves en el 1,2-3,5% de los pacientes, especialmente con la primera infusin del frmaco111, por lo que se recomienda premedicacin con antihistamnicos en todos los casos
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