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In our study, by performing metabolite pool and isotopomer labeling analyses, we found that ACTL6A increased GSH de novo synthesis mainly by regulating the synthesis of -GC, the rate-limiting step catalyzed by GCLC

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Cellular senescence and the host immune system in aging and age-related disorders

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doi: 10.1038/s41467-019-12384-2 48 RichardLCHuiWenL

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