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Front-runner Hangzhou Jiuyuan Gene Engineering has already developed one treatment that it says has "similar clinical efficacy and safety" as Ozempic and applied for approval for sale in April

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Perretti, Melanocortin Receptors as Novel Effectors of Macrophage Responses in Inflammation, Frontiers Media SA, 2011

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There, KPV inhibits the activation of NF-kB by delaying the turnover of NF-kB and IkBalpha, and it additionally suppresses the phosphorylation of MAPK, namely ERK1/2, JNK and p38

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