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Phase III randomized controlled trials demonstrated significantly increased pain-free sun exposure time with afamelanotide use in EPP patients (compared to placebo users)

Though several molecules, such as mazdutide, a GLP/glucagon dual agonist, are being studied in various phases, the first agent targeting incretins other than just GLP-1 was approved in 2022 tirzepatide [41]

rather, a healthy body achieves a balance between free radical exposure and antioxidants in order to ward off oxidative stress

Then the cells were centrifuged and washed once with 1 ml of 0.1 M borax (Sigma-Aldrich, 71997), followed by another wash with 1% BSA in PBS