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The downside is that you're layering tirzepatide's GIP effects on top of residual semaglutide (both have ~5-day half-lives, so semaglutide is still present for 2-3 weeks after your last dose)
Across all doses, female participants achieved greater percentage reductions in body weight compared to males
Nausea is often the earliest symptom, sometimes appearing just a few hours post-dose
A different semaglutide product (Wegovy) is specifically licensed for weight management in eligible patients
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