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561 fludrocortisone, a mineralocorticoid that promotes sodium and water retention to expand plasma volume, though it must be used cautiously due to the risk of supine hypertension and hypokalemia
The result, after nearly two decades of development, was exenatide (Byetta) , which received FDA approval in April 2005 as the first GLP-1 receptor agonist approved for clinical use
They measured accuracy, prediction, and clinician behavior, not whether earlier diagnosis improves how patients actually do
Fahn, S
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