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Effects of treatment with glucagon-like peptide-2 on bone resorption in colectomised patients with distal ileostomy or jejunostomy and short bowel syndrome

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1 Introduction The gutbrain peptide, glucagon-like peptide-1 (GLP-1), is encoded by the proglucagon (PPG) gene, which is expressed in the intestines and pancreas [for a review, see PPG gene is also expressed in the olfactory bulb ( The extensive physiological and behavioral effects of GLP-1 are mediated by the GLP-1 receptors (GLP-1R), which are expressed in both the central and autonomic nervous systems ( Following ingestion of a meal, the GLP-1 levels rapidly increase

Ogle CK, Ogle JD, Mao JX, et al