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Unlike older GLP-1 medications that target only one hormone, tirzepatide is the first dual GLP-1 (glucagon-like peptide 1) and GIP receptor agonist that offers greater benefits, including stronger appetite suppression, deeper metabolic changes, and more significant weight loss
Oral Semaglutide In Special Populations Semaglutide is metabolized in plasma via proteolytic cleavage of the peptide backbone and beta-oxidation of the fatty acid side chain
Landolt, H
These changes in components of appetite are suspected to be major contributors to the measured decrease in ad libitum food intake with tirzepatide compared with placebo
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