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As fat cells shrink during tirzepatide-assisted weight loss, estrogen levels may shift, particularly in postmenopausal women whose fat tissue is a primary estrogen source

They'll matter even more as the pipeline expands

Patients who developed NAION while taking Ozempic report devastating consequences: Complete loss of vision in one or both eyes Permanent visual field defects Inability to drive or work Loss of independence and quality of life Need for lifetime disability accommodations Unlike gastroparesis, which can sometimes improve after stopping the medication, vision loss from NAION is typically permanent and irreversible

Avoid it if you tend to have acid reflux