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Jaramillo MC, Zhang DD
Strategic cycling provides a middle ground for those who cant sustain continuous treatment but have capacity for intensive off-period protocols
Ann Pharmacother 46 , 15471553, (2012)
The copper peptide concentration matters significantly for under-eye use, with 0.5-1% proving optimal balance between effectiveness and minimizing irritation risk in this sensitive area, while higher concentrations (1-2%) used successfully on face may prove too irritating for periorbital application
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