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While most common variants have a modest effect size, rare coding variants identified through large-scale sequencing efforts often exhibit stronger effects and, in some cases, offer direct insight into disease mechanisms
Acknowledgements We sincerely appreciate the thoughtful and constructive comments provided by the editor and reviewers, which have greatly improved the clarity and overall quality of this manuscript
PROTACs in epigenetic cancer therapy: current status and future opportunities
Increased cell apoptosis of urothelium mediated by inflammation in interstitial cystitis/painful bladder syndrome
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