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It has long been thought depression results from a neurotransmitter imbalance, but more recent evidence suggests underlying causes such as chronic low-level inflammation, dysregulation of the stress response, altered brain cell function, and imbalance in the gut microbiome are important contributors
302 The connection between vitamin D and depression may be related to vitamin Ds immune-regulating anti-inflammatory effects, ability to promote neuroplasticity and neurogenesis, and its influence on neurotransmitter levels
Every efficacy study (obesity, liver, muscle) used subcutaneous dosing, so injection is the route with the animal evidence behind it
Molecular mechanism of noradrenaline during the stress-induced major depressive disorder
