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For the generation of FGF21 Alb-KO mice, the FGF21loxP (B6.129S6(SJL)-Fgf21tm1.2Djm/J) line was crossed with B6.Cg-Tg(Alb-cre)21Mgn/J (Alb Cre ) mice (Jackson laboratory)

Several peptides being studied have mechanisms that directly address this core problem: they promote new blood vessel formation (angiogenesis), reduce the inflammatory cascade that accelerates disc breakdown, and stimulate the cellular repair processes needed to rebuild damaged disc structures

Eur J Clin Pharmacol 81 , 15691581 (2025)

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