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This creates a metabolic disadvantage that makes plateaus more likely and harder to break
This extra gas may cause bloating and discomfort
That introduces meaningful variability: the medication has to survive stomach acid, absorb properly, and reach therapeutic levels in the bloodstreamall of which can differ from person to person
Association between albumin-bilirubin grade and plasma trough concentrations of regorafenib and its metabolites M-2 and M-5 at steady-state in Japanese patients
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