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2.5 Inflammation-associated impairment of mitochondrial metabolism is associated with reduced enteroendocrine cell markers A potential mechanism by which TNF/IFN and inflammation might affect L cell numbers is by affecting cellular metabolism and particularly mitochondrial function, including oxidative phosphorylation (OXPHOS) (15, 62, 63)
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In addition, in the contact surface some steric impediment can occur and even the antibodies can be denatured with the consequent loosening of ability to detect the antigen
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