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IL-9-secreting CD8 + Tc9 cells (a cytotoxic T lymphocyte subset) activate STAT3, upregulate fatty acid oxidation and mitochondrial activity, and exhibit reduced lipid peroxidation in the TME, thereby resisting tumor- or ROS-induced ferroptosis [91] (Fig
Below pH 6.5, acid-catalyzed hydrolysis accelerates peptide bond cleavage
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