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It is not clear whether the replacement of melanocytes of the basal cell layer of the oral epithelium lost to physiological processes of apoptosis or senescence, or to mechanical, thermal, or chemical injury is the result of cell division of mature melanocytes in the basal cell layer of the oral epithelium which still retain their capacity of replication, or a result of migration from their local niche reservoirs of melanocyte stem/progenitor cells and their subsequent proliferation [6]
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doi:10.1016/j.obpill.2025.100205 Ben-Porat T, Sherf-Dagan S, Ct M, Miner CJ, Buch A
This design allows for a convenient and controlled application on the skin, ensuring that the active ingredients are localized for optimal treatment
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