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Half-life About 159 to 195 hours (~7 to 8 days), which is why it is dosed weekly
The SURMOUNT trial showed 20% net weight loss with tirzepatide in patients with overweight/obesity, nearly as effective as metabolic surgery
Could Ozempic be used to treat liver disease in the future
Under the control of the biological clock system, the heterodimer CLOCK/BMAL1 and a series of other transcription factors are responsible for the circadian oscillation of gene expression (Takahashi et al., 2008)
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