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(2002) in the Journal of Clinical Endocrinology and Metabolism

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Amin, and those on the lower endbetween 3% and 5%are commonly used for dark spots including for melasma, post-acne marks, or sun damage, she says

Patients should be especially diligent about moisturizing daily while taking Accutane in the winter, as low humidity and cold temperatures can worsen dryness