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This process can disrupt membrane integrity, leading to impaired cellular function and cell death.Low Antioxidant Defense: Compared to other tissues, the brain has a relatively modest antioxidant defense system
T.JonesR.CoveneyC.et al
But it has a more stable metabolic byproduct that can serve as a marker for it and which is reportedly detectable for 48 to 72 hours
Within the folate cycle 5,10-methylene-THF is converted to 5-methyl-THF by methylene THF reductase which is encoded by the MTHFR gene
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